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Exendin-3 se yon peptide biyolojik aktif ki sòti nan venen mons Gila (Heloderma horridum). Li fè pati fanmi exendin nan peptides, ki estriktirèl menm jan ak peptide glucagon-like -1 (GLP-1), e li te montre efè enpòtan sou sekresyon ensilin.
Espesifikasyon
|
Sekans yon sèl lèt kòd |
HSDGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSSGAPPPS-NH2 |
|
Sekans twa lèt kòd |
His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp- Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Pro-Ser-NH2 |
|
Nimewo CAS |
130357-25-4 |
|
Fòmil molekilè |
C184H282N50O61S1 |
|
Pwa molekilè |
4202.63 |
|
Modifikasyon |
C-tèminal Amidasyon |
|
Pite |
Zòn pik pa HPLC Pi gran pase oswa egal a 95% |
|
Fòm |
Liyofilize |
|
Long Depo |
- 20 degre oswa pi ba |
| Pou itilize rechèch sèlman. | |
Referans:
1. Habener, JF, et al., "Gila Monster Venom, Gut Hormones, and Diabetes: The Winding Path to Drug Discovery," Pharmacy Times 2. Drucker, DJ, "Glucagon-like peptide 1 and its therapeutic potential," Pwosedi. nan Akademi Nasyonal Syans yo.
Baj popilè: exendin-3, exendin-3 founisè
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